Postdoctoral Position in Cancer Immunology (M/F)

Logo IC
Cette offre est expirée, il n’est plus possible de postuler
Date de clôture
Lieu(x) de travail
Paris
Secteur
Centre de Recherche
CDD
Institut Curie Research Center
Institut Curie is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness.
The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Context

Laboratory

Our group (http://ow.ly/WjoV50yVbOQ) is part of the Immunology department (Inserm U932, Paris, France) headed by Dr Ana-Maria Lennon located in the exciting professional environment of Institut Curie, one of the largest European institutions for cancer and biomedical research with strong interdisciplinary traditions.

Dr. Philippe Benaroch’s team is focused on how myeloid cells crosstalk with viruses and tumor cells, and how this interplay is regulated at the molecular level.

 

The project

Anti-cancer adoptive cell therapy using engineered myeloid cells

Solid cancers are shaped by a complex tumor microenvironment that critically impacts their growth and metastatic potential, as well as their response to therapies. Myeloid cells are major players in immune resistance and/or evasion mechanisms. They can phagocytose dead and even living cells, including tumor cells. This activity is coupled to their antigen presentation capacity which can stimulate anti-tumor immunity.

The aim of the project is to exploit functional properties of myeloid cells for antitumor cell therapies by genetic engineering. Combining state-of-the-art technologies in molecular biology and cell biology with pre-clinical experimental approaches, the candidate will develop next generation engineered myeloid cells as anti-cancer adoptive cell therapy and will decipher their mechanisms of action.

 

Candidate Profile

Training and Skills required

  • PhD & expertise with mouse preclinical models and multiparametric flow cytometry are mandatory
  • Knowledge in immunology, cancer biology & cell biology will be highly appreciated

Abiliites

  • High motivation, scientific rigor, team spirit, proficient in English, and dynamic personality
  • International applicants are well come.

 

All our opportunities are open to people with disabilities.

 

Contract information

  • Type of contract: Fixed-term contract
  • Starting date: Position available immediately
  • Duration: One year, renewable
  • Working time: Full time
  • Remuneration: according to the current grids
  • Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
  • Location of the position: Paris

 

Contact

Please send your CV, letter of motivation and 2 references, to maude.delost@curie.fr and philippe.benaroch@curie.fr

 

Publication date: 23 June 2022

Deadline for application: 31 July 2022

 

Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.

Exemple : +33112365489
Seuls les PDF sont acceptés.